Sigma-1 receptor antagonist 6 (Compound 12) is an antagonist of the Sigma-1 receptor ( σ1R ). Sigma-1 receptor antagonist 6 exerts a robust antiallodynic effect by antagonizing σ1R . Sigma-1 receptor antagonist 6 can be used in neuropathic pain animal models to alleviate mechanical allodynia induced by paclitaxel ( HY-B0015 ).
Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Sigma Receptor
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