PROTAC SMARCA2/4 degrader-28

Overview

PROTAC SMARCA2/4 degrader-28 is a heterobifunctional PROTAC degrader targeting SMARCA2 and SMARCA4 . PROTAC SMARCA2/4 degrader-28 forms a ternary complex with CRL2 VHL E3 ligase and SMARCA2 or SMARCA4, mediating the ubiquitination and degradation of SMARCA2, while acting as a partial degrader of SMARCA4. PROTAC SMARCA2/4-degrader-28 can be used in cancer-related research. (Pink: SMARCA2 and SMARCA4 ligand ( HY-13030 ); Blue: VHL ligand ( HY-125845 ); Black: linker ( HY-159680 )).

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > PROTAC | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > PROTACs | Products > Signaling Pathways > SWI/SNF Complex

Product Information

• Catalog No.: HY-162835
• CAS No.: 2409844-88-6
• Molecular Formula: C54H68ClN9O11S2
• Molecular Weight: 1118.75
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source