FO-4-15

Overview

FO-4-15 is an mGluR1/CaMKIIα activator. FO-4-15 has a protective effect against H 2 O 2 in human neuroblastoma (SH-SY5Y) cells. FO-4-15 can improve cognitive impairment in Alzheimer’s disease mice by activating the mGluR1/CaMKIIα pathway, and can reduce Aβ accumulation, hyperphosphorylated Tau , and synaptic damage.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > mGluR | Products > Signaling Pathways > CaMK | Products > Signaling Pathways > Tau Protein

Product Information

• Catalog No.: HY-162860
• CAS No.: 1030759-58-0
• Molecular Formula: C18H20N4O4S
• Molecular Weight: 388.44
• Purity: 99.45%
• Storage: Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 1.25 mg/mL (3.22 mM); Clear solution
• Availability: In-stock

Source

Original product source