NLRP3-IN-28 (compound N77) is a potent inhibitor of NLRP3 . NLRP3-IN-28 inhibits Nigericin ( HY-127019 )-induced pyroptosis with an EC 50 of 0.07μM. NLRP3-IN-28 alleviates the inflammatory reaction in vivo.
Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > Immunology/Inflammation | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > NOD-like Receptor (NLR) | Products > Signaling Pathways > Pyroptosis
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