COX-2/15-LOX-IN-5 (Compound 4f) is a dual inhibitor of COX-2/15-LOX . COX-2/15-LOX-IN-5 attenuates increased NF-κB activation in RAW 264.7 macrophages mediated by lipopolysaccharide ( HY-D1056 ). COX-2/15-LOX-IN-5 has anti-inflammatory and antioxidant activities.
Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > Immunology/Inflammation | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > NF-κB | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > COX | Products > Signaling Pathways > Lipoxygenase | Products > Signaling Pathways > NF-κB
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