HDAC6-IN-34

Overview

HDAC6-IN-34 (compound 21) is an oral active and selective HDAC6 inhibitor with the IC 50 of 18 nM. HDAC6-IN-34 increases the acetylation level of tubulin without affecting histone acetylation in cutaneous T-cell lymphoma cells and inhibits TNF-α secretion in LPS ( HY-D1056 )-stimulated macrophage cells. HDAC6-IN-34 shows excellent anti-arthritic efficacy in rat.

Application

Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Epigenetics | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > HDAC

Product Information

• Catalog No.: HY-163368
• CAS No.: 1432508-73-0
• Molecular Formula: C18H18F3N3O3
• Molecular Weight: 381.35
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source