C5aR1 antagonist 1 (Compound 7e) is an orally active C5a receptor 1 ( C5aR1 ) antagonist. C5aR1 antagonist 1 is active in DISCO and migration assays, with IC 50 values of 38 nM and 17 nM, respectively. C5aR1 antagonist 1 can be used for the research of acute and chronic inflammatory diseases.
Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > Immunology/Inflammation | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > Complement System
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