C5aR1 antagonist 2

Overview

C5aR1 antagonist 2 (Compound 6a) is an orally active C5a receptor 1 ( C5aR1 ) antagonist that shows efficacy in inhibiting the C5a-induced neutrophil count increase. C5aR1 antagonist 2 is potent in the DISCO and migration assays, with IC 50 values of 21 and 3 nM, respectively. C5aR1 antagonist 2 can be used for the research of acute and chronic inflammatory diseases.

Application

Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > Immunology/Inflammation | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > Complement System

Product Information

• Catalog No.: HY-163379
• CAS No.: 2365161-92-6
• Molecular Formula: C29H30F3N3O2
• Molecular Weight: 509.56
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source