PROTAC NAMPT Degrader-1

Overview

PROTAC NAMPT Degrader-1 is a potent PROTAC targeting NAMPT with a DC 50 value of 217 nM. PROTAC NAMPT Degrader-1 has anti-proliferative activity with an IC 50 value of 0.12μM against A2780 cells. (Structure Note: PINK, NAMPT activator ( HY-163445 ); Blue, VHL ligand ( HY-163440 ); Black, linker).

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > PROTAC | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > PROTACs | Products > Signaling Pathways > NAMPT

Product Information

• Catalog No.: HY-163440
• CAS No.: 3102963-15-2
• Molecular Formula: C57H69N13O8S2
• Molecular Weight: 1128.37
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source