pan-HCN-IN-1

Overview

pan-HCN-IN-1 (Compound J&J12e) is an inhibitor for hyperpolarization-activated and cyclic-nucleotide-gated 1 ( HCN1 ) ion channel, with IC 50 of 58 nM. pan-HCN-IN-1 reduces the voltage sag response and enhances EPSP summation in ex vivo rats brain slices.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > HCN Channel

Product Information

• Catalog No.: HY-163455
• CAS No.: 1334308-63-2
• Molecular Formula: C23H37N3O2
• Molecular Weight: 387.56
• Purity: 99.84%
• Storage: Pure form -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 5 mg/mL (12.90 mM); Clear solution
• Availability: In-stock

Source

Original product source