JYQ-194

Overview

JYQ-194 is a PROTAC degrader that selectively induces PARK7 degradation by recruiting cereblon . JYQ-194 induces proteasome-dependent degradation of PARK7 in human tumor cells. JYQ-194 is applicable to research related to Parkinson's disease and cancer . (Pink: PINK1/Parkin ligand ( HY-163563 ); Blue: Cereblon ligand ( HY-10984 ); Black: linker ( HY-W017440 )).

Application

Products | Products > Disease Areas > Parkinson's Disease | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Cancer | Products > Disease Areas > Neurodegenerative Disease | Products > Signaling Pathways > PROTAC | Products > Signaling Pathways > Neuronal Signaling | Products > Signaling Pathways > Autophagy | Products > Research Areas > Neurological Disease | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > PROTACs | Products > Signaling Pathways > PINK1/Parkin

Product Information

• Catalog No.: HY-163564
• CAS No.: 3117543-71-9
• Molecular Formula: C39H38FN11O8S
• Molecular Weight: 839.85
• Purity: 98.05%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 2.5 mg/mL (2.98 mM); Clear solution
• Availability: In-stock

Source

Original product source