BIIB129

Overview

BIIB129 is a covalent, selective, small molecule inhibitor of Bruton's tyrosine kinase ( BTK ) capable of penetrating the blood-brain barrier. BIIB129 inhibits the activity of BTK by covalently binding to Cys481 in BTK , thereby affecting the function of B cells and myeloid cells. BIIB129 can be used in multiple sclerosis (MS) research.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Btk

Product Information

• Catalog No.: HY-163565
• CAS No.: 2770960-52-4
• Molecular Formula: C19H22N6O2
• Molecular Weight: 366.42
• Purity: 99.54%
• Storage: 4°C, stored under nitrogen * In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
• Solubility: ≥ 2.5 mg/mL (6.82 mM); Clear solution
• Availability: In-stock

Source

Original product source