Omtriptolide sodium

Overview

Omtriptolide sodium (PG490-88Na) is a derivative of Triptolide ( HY-32735 ). Omtriptolide sodium exhibits significant immunosuppressive, anti-fibrotic and anti-inflammatory properties. The mechanism of action of Omtriptolide sodium is diverse, including inhibiting T cell activation and proliferation, inducing T cell apoptosis ( apoptosis ), blocking fibroblast maturation/proliferation, inhibiting TGF-β mRNA expression, and suppressing pro-inflammatory cytokines (such as IL-2 , IFN-γ , TNF-α ) by blocking transcription factors such as NF-κB . Omtriptolide sodium can be used for research on obstructive airway diseases, pulmonary fibrosis and graft-versus-host disease.

Application

Products | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > TGF-beta/Smad | Products > Signaling Pathways > NF-κB | Products > Signaling Pathways > Immunology/Inflammation | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > IFNAR | Products > Signaling Pathways > TNF Receptor | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > TGF-β Receptor | Products > Signaling Pathways > NF-κB | Products > Signaling Pathways > Interleukin Related

Product Information

• Catalog No.: HY-16362
• CAS No.: 195883-09-1
• Molecular Formula: C24H27NaO9
• Molecular Weight: 482.46
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source