AHR antagonist 8

Overview

AHR antagonist 8 (compound SG-02) is a regulator of utrophin , a homolog of dystrophin , and an AhR antagonist (Kd: 41.68 nM). Studies have shown that 800 nM of AHR antagonist 8 can upregulate utrophin by 2.7 times. AHR antagonist 8 also stimulates increased MyHC expression, suggesting that it has the potential to enhance myogenesis. After ADME evaluation, AHR antagonist 8 also has a certain oral bioavailability.

Application

Products | Products > Disease Areas > Others | Products > Signaling Pathways > Immunology/Inflammation | Products > Signaling Pathways > Cytoskeleton | Products > Research Areas > Others | Products > Signaling Pathways > Aryl Hydrocarbon Receptor | Products > Signaling Pathways > Dystrophin

Product Information

• Catalog No.: HY-163665
• CAS No.: 3052113-26-2
• Molecular Formula: C16H14FN3O2S
• Molecular Weight: 331.36
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source