TLR7 agonist 21

Overview

TLR7 agonist 21 (Compound 27B) is a selective agonist for Toll-like receptor 7 ( TLR7 ), with an EC 50 of 17.53 nM (for human TLR7 ) and 41.7 nM (for mouse TLR7 ). TLR7 agonist 21 stimulates the secretion of pro-inflammatory cytokines, such as IL-6 , TNF-α, IFN-α1, and IL-4 . TLR7 agonist 21 acts as a vaccine adjuvant , increases levels of IgG and IgA , and protects the mouse from influenza virus infections.

Application

Products | Products > Disease Areas > Infection | Products > Signaling Pathways > Immunology/Inflammation | Products > Research Areas > Infection | Products > Signaling Pathways > Toll-like Receptor (TLR)

Product Information

• Catalog No.: HY-163670
• CAS No.: 3040038-00-1
• Molecular Formula: C22H33N7O
• Molecular Weight: 411.54
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source