NLRP3-IN-42 (compound H28) is a potent NLRP3 inhibitor with an K D value of 1.15 µM. NLRP3-IN-42 decreases the LPS ( HY-D1056 ) induced protein expression of cleaved-caspase-1 (p20). NLRP3-IN-42 selectively inhibits IL-1β release.
Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > Immunology/Inflammation | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > NOD-like Receptor (NLR) | Products > Signaling Pathways > Interleukin Related
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