TMV-IN-9 (compound A6) is an antiviral agent that displays excellent inactivating against tobacco mosaic virus ( TMV ) with an EC 50 of 62.8 μg/mL. TMV-IN-9 shows strong binding capacity to TMV coat protein with a binding affinity value of 1.862 μM. TMV-IN-9 obviously destroys the integrity of the TMV particles and blocked the virus from infecting the host.
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