Fraxinellone analog 1 (compound 2) is a potent and rapid activator of the Nrf2 mediated antioxidant defense system, which protects against glutamate-mediated excitotoxicity and induces the expression of antioxidant genes Gpx4 , Sod1 , and Nqo1 . Fraxinellone analog 1 has neuroprotective effects and regulatory effects against oxidative stress and inflammation, and can be used in the study of neurodegenerative diseases.
Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > NF-κB | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Keap1-Nrf2
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