CDK2 degrader 1

Overview

CDK2 degrader 1 (Compound 3) is a selective CDK2 molecular glue degrader with a D max ( CDK2 ) of > 80% and a K i (CRBN) > 1 μM. CDK2 degrader 1 binds to cereblon to induce ubiquitination and subsequent proteasomal degradation of the CDK2 . CDK2 degrader 1 is used in the research of a wide range of cancers.

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > PROTAC | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Molecular Glues | Products > Signaling Pathways > CDK

Product Information

• Catalog No.: HY-163814
• CAS No.: 3036604-59-5
• Molecular Formula: C23H27F2N3O4
• Molecular Weight: 447.47
• Purity: 99.74%
• Storage: 4°C, protect from light, stored under nitrogen * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
• Solubility: ≥ 2.5 mg/mL (5.59 mM); Clear solution
• Availability: In-stock

Source

Original product source