VU0359595 (CID-53361951; ML-270) is a potent and selective pharmacological phospholipase D1 ( PLD1 ) inhibitor with an IC 50 of 3.7 nM. VU0359595 is >1700-fold selective for PLD1 over PLD2 ( IC 50 of 6.4 μM). VU0359595 can be used for the research of cancer , diabetes, neurodegenerative and inflammatory diseases.
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