PROTAC NCOA4 degrader-1

Overview

PROTAC NCOA4 degrader-1 is a VHL-based PROTAC NCOA4 degrader. PROTAC NCOA4 degrader-1 is a ferroptosis inhibitor. PROTAC NCOA4 degrader-1 reduces Fe 2+ elevation, ROS production, MDA content and PTGS2 mRNA expression. PROTAC NCOA4 degrader-1 ameliorates liver damage in a CCl 4 -induced acute liver injury model. PROTAC NCOA4 degrader-1 can be used for the researches of inflammation and immunology.

Application

Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > PROTAC | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Immunology/Inflammation | Products > Signaling Pathways > NF-κB | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > PROTACs | Products > Signaling Pathways > Ferroptosis | Products > Signaling Pathways > Reactive Oxygen Species (ROS)

Product Information

• Catalog No.: HY-163897
• CAS No.: 3098187-24-4
• Molecular Formula: C62H80N10O9S
• Molecular Weight: 1141.43
• Purity: 99.75%
• Storage: 4°C, protect from light, stored under nitrogen * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
• Solubility: ≥ 2.5 mg/mL (2.19 mM); Clear solution
• Availability: In-stock

Source

Original product source