SUN-1334H free base

Overview

SUN-1334H free base is an orally active inhibitor for histamine H1 receptor, with an IC 50 of 20.3 nM and K i of 9.7 nM. SUN-1334H free base inhibits histamine-induced contractions of isolated guinea-pig ileum with an IC 50 of 0.198 μM. SUN-1334H free base inhibits histamine-induced bronchoconstriction in guinea pigs, histamine-induced skin wheals in beagle dogs, and ovalbumin-induced rhinitis in guinea pigs.

Application

Products | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Neuronal Signaling | Products > Signaling Pathways > Immunology/Inflammation | Products > Research Areas > Inflammation/Immunology | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > Histamine Receptor | Products > Signaling Pathways > Dopamine Receptor | Products > Signaling Pathways > Adrenergic Receptor | Products > Signaling Pathways > Sigma Receptor

Product Information

• Catalog No.: HY-164010
• CAS No.: 607737-00-8
• Molecular Formula: C23H26F2N2O3
• Molecular Weight: 416.46
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source