RS 45041-190 hydrochloride is a high-affinity ligand for I2 imidazoline receptors , with the pK i s of 8.66, 9.37, 9.32, and 8.85 in rat, rabbit, dog and baboon kidney, respectively. RS 45041-190 hydrochloride shows moderate potency for the inhibition of monoamine oxidase A in vitro ( pIC 50 = 6.12), but had much lower potency for monoamine oxidase B ( pIC 50 = 4.47).
Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Imidazoline Receptor
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