LK-2

Overview

LK-2 is an antagonist for ASIC1a with a K d of 1.9 μM. LK-2 reduces glutamate-induced ASIC1a current-enhancement with an IC 50 of 6.6 μM. LK-2 exhibits neuroprotective efficacy in mouse ischemic stroke model, with improved motor and coordination skills. LK-2 is blood-brain barrier (BBB) penetrable.

Application

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Product Information

• Catalog No.: HY-164284
• CAS No.: 2649762-09-2
• Molecular Formula: C12H17N2O5P
• Molecular Weight: 300.25
• Purity: 98.83%
• Storage: -20°C, sealed storage, away from moisture and light * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
• Availability: In-stock

Source

Original product source