PROTAC PARP1 degrader-2

Overview

PROTAC PARP1 degrader-2 (Compound 72) is a PROTAC degrader for PARP with a DC 50 <10 nM in MDA-MB-231 cell. PROTAC PARP1 degrader-2 inhibits the cell viability of MDA-MB-436 with an IC 50 <100 nM. (Pink: PARP ligand ( HY-160937 ); Blue: VHL ligand ( HY-W998262 ); Black: linker).

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > PROTAC | Products > Signaling Pathways > Epigenetics | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Signaling Pathways > PROTACs | Products > Signaling Pathways > PARP

Product Information

• Catalog No.: HY-164306
• CAS No.: 2923686-62-6
• Molecular Formula: C38H37F2N9O6
• Molecular Weight: 753.75
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source