GPR17 modulator-1 (Compound 2-046) is a modulator for G protein-coupled receptor 17 GPR17 , with an IC 50 <10 nM for hGPR17 in CHO. GPR17 modulator-1 exhibits moderate pharmacokinetic characteristics in mice. GPR17 modulator-1 ix blood-brain barrier (BBB) permeable.
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