NS3736

Overview

NS3736 is an orally effective chloride channel inhibitor that can be used for the research of osteoporosis. NS3736 targets the CIC-7 channel in osteocytes, blocks osteoclast acidification and resorption in vitro, with IC 50 =30 μM. In a rat model of ovariectomy-induced osteoporosis, NS3736 can enhance bone strength and bone density.

Application

Products | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Research Areas > Metabolic Disease | Products > Signaling Pathways > Chloride Channel

Product Information

• Catalog No.: HY-164532
• CAS No.: 265646-94-4
• Molecular Formula: C15H9BrClF3N6O
• Molecular Weight: 461.62
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source