NCS-MP-NODA (NODA-Bz-SCN) is a NODA-derived bifunctional chelator. NCS-MP-NODA can conjugate with biomolecules including the RGD tripeptide, and is used for aluminum-[ 18 F] fluoride-based positron emission tomography (PET) radiolabeling. NCS-MP-NODA can conjugate with the free lysine amino group of the PD-L1 -specific peptide DK221 to generate DK222, which can be radiolabeled with 18 F to form [ 18 F]DK222. NCS-MP-NODA can be used in studies related to triple-negative breast cancer , melanoma and colon cancer .
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