Lumateperone metabolite 1 (Formula T) is a metabolite of Lumateperone ( HY-17637 ). Lumateperone (ITI-007) is an orally active 5-HT2A receptor antagonist ( K i = 0.54 nM), a partial agonist of presynaptic D2 receptors and an antagonist of postsynaptic D2 receptors ( K i = 32 nM), and a dopamine D1 receptor modulator
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