FXR agonist 12

Overview

FXR agonist 12 (Compound C7) is the orally active agonist for FXR . FXR agonist 12 down-regulates bile acid synthesis-related genes, and up-regulates bile acid transport-related genes in HepG2 cells. FXR agonist 12 improves ANIT-induced cholestasis, ameliorates the liver damage and fibrosis in mouse NASH models.

Application

Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > FXR

Product Information

• Catalog No.: HY-164799
• CAS No.: 1831862-88-4
• Molecular Formula: C26H44O3
• Molecular Weight: 404.63
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source