(±)2-(14,15-Epoxyeicosatrienoyl) glycerol

Overview

(±)2-(14,15-Epoxyeicosatrienoyl) glycerol ((±)2-14,15-EG) is a novel CYP450 metabolite of 2-Arachidonoyl glycerol (2-AG) in the kidney. (±)2-(14,15-Epoxyeicosatrienoyl) glycerol is a potent mitogen for renal epithelial cells, increasing DNA synthesis in LLCPKcl4 cells. (±)2-(14,15-Epoxyeicosatrienoyl) glycerol activates the metalloprotease ADAM17 , which cleaves proTGF-α and releases TGF-α as a ligand that initiates the EGFR-ERK signalling pathway.

Application

Products | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Research Areas > Metabolic Disease | Products > Signaling Pathways > DNA/RNA Synthesis

Product Information

• Catalog No.: HY-165060
• CAS No.: 848667-56-1
• Molecular Formula: C23H38O5
• Molecular Weight: 394.54
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source