(S)-VU0637120

Overview

(S)-VU0637120 is a Y4R antagonist that effectively reduces the binding response of its endogenous ligand, pancreatic polypeptide (PP), on Y4R, with an IC 50 value of 2.7 μM. (S)-VU0637120 binds to the allosteric site of Y4R, which is located in the core region of the Y4R transmembrane structure, near the binding pocket of pancreatic polypeptide (PP), with a K B value of 300-400 nM. (S)-VU0637120 holds potential for research in the field of metabolic diseases.

Application

Products | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Metabolic Disease | Products > Signaling Pathways > Neuropeptide Y Receptor

Product Information

• Catalog No.: HY-165125
• CAS No.: 1175940-86-9
• Molecular Formula: C16H19N3O5S2
• Molecular Weight: 397.47
• Purity: 99.5%
• Storage: Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Availability: In-stock

Source

Original product source