NIR-BG2

Overview

NIR-BG2 is a fluorescent indicator targeting senescence-associated β-galactosidase (SA-β-Gal) . NIR-BG2 contains a hemicyanine fluorophore caged by SA-β-Gal; cleavage of its β-galactosyl group by SA-β-Gal generates an electrophilic quinone methide, which can form covalent bonds with adjacent proteins to achieve long-term signal retention. NIR-BG2 activates a near-infrared fluorescent signal upon recognition of SA-β-Gal. NIR-BG2 can be used for non-invasive in vivo imaging of cellular senescence in mouse xenograft models. The excitation/emission wavelengths are 675/708 nm.

Application

Products | Products > Disease Areas > Others | Products > Signaling Pathways > Others | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Others | Products > Signaling Pathways > Fluorescent Dye | Products > Signaling Pathways > Glycosidase

Product Information

• Catalog No.: HY-165424
• CAS No.: 3036456-18-2
• Molecular Formula: C42H46F2NO8+
• Molecular Weight: 730.81
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source