MMV665917 is an orally active piperazine derivative with anti- Cryptosporidium parvum activity with an EC 90 of 15 μM. MMV665917 significantly reduces the parasite load in a porcine model infected with C. hominis , decreases ovarian excretion, alleviates diarrhea symptoms and reduces intestinal mucosal damage. MMV665917 can be used for research on Cryptosporidium parvum disease.
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