Camptothecin

Overview

Camptothecin (CPT), a kind of alkaloid, is a DNA topoisomerase I ( Topo I ) inhibitor with an IC 50 of 679 nM. Camptothecin (CPT) exhibits powerful antineoplastic activity against colorectal, breast, lung and ovarian cancers, modulates hypoxia-inducible factor-1α ( HIF-1α ) activity by changing microRNAs (miRNA) expression patterns in human cancer cells.

Application

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Product Information

• Catalog No.: HY-16560
• CAS No.: 7689-03-4
• Molecular Formula: C20H16N2O4
• Molecular Weight: 348.35
• Purity: 99.77%
• Storage: 4°C, protect from light * In solvent : -80°C, 1 year; -20°C, 6 months (protect from light)
• Solubility: 10 mg/mL (28.71 mM); Suspended solution; Need ultrasonic
• Availability: In-stock

Source

Original product source