Camptothecin (Standard) (Campathecin (Standard)) is the analytical standard of Camptothecin ( HY-16560 ). This product is intended for research and analytical applications. Camptothecin (CPT), a kind of alkaloid, is a DNA topoisomerase I ( Topo I ) inhibitor with an IC 50 of 679 nM. Camptothecin (CPT) exhibits powerful antineoplastic activity against colorectal, breast, lung and ovarian cancers, modulates hypoxia-inducible factor-1α ( HIF-1α ) activity by changing microRNAs (miRNA) expression patterns in human cancer cells.
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