(R)-LY-41

Overview

(R)-LY-41, R-enantiomer of LY-41 ( HY-165624 ), is 2-Sminotetralin ( HY-W022362 ) derivative and 8-OH-DPAT ( HY-112061 ) analogue. (R)-LY-41 is a potent and selective 5-HT1A receptor agonist. (R)-LY-41 can reduce the accumulation of 5-hydroxytryptophan (the precursor for 5-HT synthesis) in the rat brain induced by decarboxylase inhibitors (NSD 1015). (R)-LY-41 can lower the body temperature of rats and inhibit the escape response from the cage. (R)-LY-41 can induce the 5-HT behavioral syndrome but is weaker than (S)-LY-41 ( HY-165624A ). (R)-LY-41 can be used for the research of neurological disease , such as depression and anxiety.

Application

Products | Products > Disease Areas > Anxiety or Fear-Related Disease | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Depression | Products > Signaling Pathways > Others | Products > Signaling Pathways > Neuronal Signaling | Products > Signaling Pathways > GPCR/G Protein | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Drug Isomer | Products > Signaling Pathways > Drug Derivative | Products > Signaling Pathways > 5-HT Receptor

Product Information

• Catalog No.: HY-165624B
• CAS No.: 136296-43-0
• Molecular Formula: C18H27NO
• Molecular Weight: 273.41
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source