A-61603

Overview

A-61603 is a selective α 1 A/α 1 a-adrenergic receptor agonist with K i of 8.89 nM for rat submaxillary gland α1A, K i of 30.5 nM for cloned bovine α1a. A-61603 potentiates Ca 2+ transients with EC 50 of 6.9 nM. A-61603 stimulates phosphoinositide hydrolysis, induces contractile responses in vas deferens, prostate strips, and spleen strips, and exhibits low activity in aortic rings. A-61603 can be used for research on adrenergic function.

Application

Products | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Disease Areas > Hypothalamic-Pituitary-Adrenal Regulation | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Endocrinology | Products > Signaling Pathways > Adrenergic Receptor

Product Information

• Catalog No.: HY-101366
• CAS No.: 107756-30-9
• Molecular Formula: C14H20BrN3O3S
• Molecular Weight: 390.30
• Purity: 99.34%
• Storage: -20°C, sealed storage, away from moisture * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
• Availability: In-stock

Source

Original product source