AM404, an inhibitor of endocannabinoid reuptake , blocks anandamide transport with IC 50 values in the low micromolar range. AM404 is able to relax rat isolated hepatic arteries contracted with Phenylephrine, with a pEC 50 value of 7.4 (corresponding to an EC 50 of 0.04 μM). Neuroprotective Effect.
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