CGP 12177

Overview

CGP 12177 ((±)-CGP 12177) is a β-Adrenergic receptor ( β-AR ) ligand. CGP 12177 is a β 3 -AR ( K i = 88 nM) agonist with β 1 /β 2 -AR ( K i = 0.9 nM for β 1 ; K i = 4 nM for β 2 ) antagonist action. CGP 12177 exhibits partial agonist properties for α 1 -AR in rat pulmonary artery. CGP 12177 regulates the expression of ucp and leptin genes in NMRI mice adipose tissues. CGP 12177 can be used for cardiovascular and metabolic disease research.

Application

Products | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Metabolic Disease | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > Adrenergic Receptor

Product Information

• Catalog No.: HY-101393
• CAS No.: 81047-99-6
• Molecular Formula: C14H21N3O3
• Molecular Weight: 279.33
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source