CGP 12177 hydrochloride

Overview

CGP 12177 ((±)-CGP 12177) hydrochloride is a β-Adrenergic receptor ( β-AR ) ligand. CGP 12177 hydrochloride is a β 3 -AR ( K i = 88 nM) agonist with β 1 /β 2 -AR ( K i = 0.9 nM for β 1 ; K i = 4 nM for β 2 ) antagonist action. CGP 12177 hydrochloride exhibits partial agonist properties for α 1 -AR in rat pulmonary artery. CGP 12177 hydrochloride regulates the expression of ucp and leptin genes in NMRI mice adipose tissues. CGP 12177 hydrochloride can be used for cardiovascular and metabolic disease research [1][2][3][4] .

Application

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Product Information

• Catalog No.: HY-101393A
• CAS No.: 64208-32-8
• Molecular Formula: C14H22ClN3O3
• Molecular Weight: 315.80
• Purity: 99.57%
• Storage: -20°C, sealed storage, away from moisture * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
• Availability: In-stock

Source

Original product source