PNU-159682 (GMP)

Overview

PNU-159682 GMP is a GMP grade PNU-159682 ( HY-16700 ). PNU-159682 , a metabolite of the anthracycline Nemorubicin, is a highly potent DNA topoisomerase II inhibitor with excellent cytotoxicity. PNU-159682 acts as a more potent and tolerated ADC cytotoxin than Doxorubicin for ADC synthesis. PNU-159682 can be used in EDV-nanocell technology to overcome agent resistance.

Application

Products | Products > GMP Small Molecules | Products > Disease Areas > Cancer | Products > Signaling Pathways > Antibody-Drug Conjugate/ADC Related | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Drug Resistance | Products > Signaling Pathways > ADC Payloads | Products > Signaling Pathways > Topoisomerase

Product Information

• Catalog No.: HY-16700G
• CAS No.: 202350-68-3
• Molecular Formula: C32H35NO13
• Molecular Weight: 641.62
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source