Pulsatilla saponin D, isolated from the root of Pulsatilla koreana, has exhibited potential beneficial effects as a chemopreventive agent for critical health conditions including cancer. It effectively inhibited the growth of gastric cancer cells. It also strongly suppressed the growth and proliferation of 5 human pancreatic cancer cell lines (MIAPaCa-2, BXPC-3, PANC-1, AsPC-1 and HPAC) and colon cancer cells and induced their apoptosis. Besides, it showed anti-angiogenic activity by decreasing the expression of HIF-1α and VEGF.
Products > Chemistry > Natural Compounds | Products > Drug Discovery > Inhibitor | Triterpenoids
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