(S)-(-)-5-Fluorowillardiine

Overview

(S)-(-)-5-Fluorowillardiine ((5S)-Fluorowillardiine; (S)-5-Fluorowillardiine) is a potent, highly selective non-NMDA ionotropic glutamate receptor ( iGluR , AMPA/Kainate receptor ) agonist . (S)-(-)-5-Fluorowillardiine activates high-affinity AMPA-preferring receptors ( EC 50 = 0.70 μM) and low-affinity kainate-preferring receptors ( EC 50 = 170 μM), thereby inducing biphasic dose-dependent neurotoxicity/excitotoxicity. (S)-(-)-5-Fluorowillardiine is applicable to research related to schizophrenia, temporal lobe epilepsy, and bipolar disorder.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Schizophrenia | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > iGluR

Product Information

• Catalog No.: HY-16713
• CAS No.: 140187-23-1
• Molecular Formula: C7H8FN3O4
• Molecular Weight: 217.15
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
• Availability: In-stock

Source

Original product source