(S)-(-)-5-Fluorowillardiine (hydrochloride)

Overview

(S)-(-)-5-Fluorowillardiine ((5S)-Fluorowillardiine; (S)-5-Fluorowillardiine) hydrochloride is a potent, highly selective non-NMDA ionotropic glutamate receptor ( iGluR , AMPA/Kainate receptor ) agonist . (S)-(-)-5-Fluorowillardiine hydrochloride activates high-affinity AMPA-preferring receptors ( EC 50 = 0.70 μM) and low-affinity kainate-preferring receptors ( EC 50 = 170 μM), thereby inducing biphasic dose-dependent neurotoxicity/excitotoxicity. (S)-(-)-5-Fluorowillardiine hydrochloride is applicable to research related to schizophrenia, temporal lobe epilepsy, and bipolar disorder.

Application

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Product Information

• Catalog No.: HY-16713A
• CAS No.: 1321546-70-6
• Molecular Formula: C7H9ClFN3O4
• Molecular Weight: 253.62
• Purity: 99.03%
• Storage: 4°C, sealed storage, away from moisture * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
• Availability: In-stock

Source

Original product source