Denagliptin

Overview

Denagliptin (GSK823093) is a small molecule dipeptidyl peptidase IV ( DPP-4 ) inhibitor with activity for the suppression of endocrine and metabolic diseases. Denagliptin can be used to study type 2 diabetes. Denagliptin is stable in the solid state but degrades in solution and in mixtures with various excipients. Denagliptin also exhibits degradation in capsules, mainly through cyclization reactions to form (3S,7S,8aS) aminoamines to provide further synthetic materials . The degradation pathway of Denagliptin was elucidated, providing data to support its formulation development and regulatory filings.

Application

Products | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Metabolic Disease | Products > Signaling Pathways > Endogenous Metabolite

Product Information

• Catalog No.: HY-167680
• CAS No.: 483369-58-0
• Molecular Formula: C20H18F3N3O
• Molecular Weight: 373.37
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
• Availability: In-stock

Source

Original product source