DMP-728 free base

Overview

DMP-728 free base (XL-118) is a highly potent and selective GPIIb/IIIa antagonist with antiplatelet and antithrombotic activities. DMP-728 free base can inhibit ADP-induced human platelet aggregation in vitro, with an IC 50 of 46 nmol/L, and can significantly reduce the interaction between fibrinogen and human platelets or Binding of purified human GPIIb/IIIa receptors. DMP-728 free base exhibits dose-dependent antiplatelet effects in anesthetized mongrel dogs, effectively inhibiting ADP-induced platelet aggregation and prolonging template bleeding time.

Application

Products | Products > Peptides | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Research Areas > Cardiovascular Disease

Product Information

• Catalog No.: HY-167848
• CAS No.: 153345-74-5
• Molecular Formula: C25H36N8O7
• Molecular Weight: 560.60
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source