GA 0113 is a potent and orally active angiotensin II (Ang II) AT1-receptor antagonist. GA 0113 inhibits the Ang II ( HY-13948 )-induced pressor response with ID 50 of 0.032 mg/kg and dose-dependently increases plasma renin activity for 48 h.
Products | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > Angiotensin Receptor
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