JNJ-47965567

Overview

JNJ-47965567 is a centrally permeable, high-affinity, selective P2X7 antagonist, with pK i s of 7.9 and 8.7 for human and rat P2X7, respectively. JNJ-47965567 can be used to probe the role of central P2X7 in rodent models of CNS pathophysiology.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > P2X Receptor

Product Information

• Catalog No.: HY-101418
• CAS No.: 1428327-31-4
• Molecular Formula: C28H32N4O2S
• Molecular Weight: 488.64
• Purity: 99.87%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 2.5 mg/mL (5.12 mM); Clear solution
• Availability: In-stock

Source

Original product source