PROTAC EZH2 Degrader-3

Overview

PROTAC EZH2 Degrader-3 is a EZH2 PROTAC degrader. PROTAC EZH2 Degrader-3 induces the global degradation of the PRC2 complex (including EZH2 , SUZ12 , EED , RbAp48 ) via the ubiquitin-proteasome pathway and downregulates H3K27me3 levels. PROTAC EZH2 Degrader-3 inhibits cancer cell proliferation and induces their apoptosis . PROTAC EZH2 Degrader-3 can be used in research related to lymphoblastoma and diffuse large B-cell lymphoma. (Pink: Apoptosis and EZH2 ligand ( HY-13803 ); Blue: Cereblon ligand ( HY-W884255 ); Black: linker ( HY-W361751 )).

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > PROTAC | Products > Signaling Pathways > Epigenetics | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Research Areas > Cancer | Products > Signaling Pathways > PROTACs | Products > Signaling Pathways > Histone Methyltransferase | Products > Signaling Pathways > Apoptosis

Product Information

• Catalog No.: HY-168131
• CAS No.: 3098718-46-5
• Molecular Formula: C56H68N8O8
• Molecular Weight: 981.19
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source